AN INTRODUCTION TO CHAMPIONS’ PERSONALIZED CANCER TREATMENT

Champions' exclusive, personalized cancer treatment options can empower you and your physician through:

Banking of your living tumor to enable future studies if needed, for you and your family
Optimization of treatment choices including simultaneous evaluation of the effectiveness of numerous anti-cancer drugs on your Tumorgraft
Development of a targeted personalized cancer vaccine directly from your tumor
Review of your case and tumor-specific data by a panel of international experts working with your physician, dedicated to improving your outcome

LIVE TUMOR BANKING

Live Tumor Banking is the collection, growth and storage of your living tumor tissue.

Tumors are typically stored through processes that kill the tumor cells and limit future testing options. Live Tumor Banking preserves and stores your living tumor as taken from your body AND utilizes a new process called “tumor grafting” to grow your living tumor in a manner similar to the way it grows in your body. This “Personalized Tumorgraft” process enables future testing that may help guide your treatment.

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PERSONALIZED TUMORGRAFT

Personalized Tumorgrafts represent a novel approach to personalized cancer treatment and are showing promise in predicting a patient's clinical response to drug therapies. A Personalized Tumorgraft is a sample of the patient's living tumor that is grown and tested in our facilities. By utilizing the Personalized Tumorgraft implantation program, the cancer treatment selected for the patient by his/her physician may be more likely to be successful, sparing the patient from undergoing therapy that may not be optimal for that specific cancer. Importantly, Champions maintains the patient's living Tumorgraft for future testing studies as the patient's condition changes, new technologies emerge, or in case a family member is diagnosed with cancer.

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PERSONALIZED VACCINE

A therapeutic cancer vaccine may be developed from the patient's tumor to help provide the most personalized cancer treatment available. Tumor cells from the Personalized Tumorgraft (cells from the patient's tumor) are genetically modified, then used to stimulate a patient's immune system to recognize and, if possible, attack the patient's cancer cells. Personalized Vaccines are designed to treat cancers that have already occurred. They are intended to delay or stop cancer cell growth; cause tumor shrinkage; prevent cancer from coming back; or eliminate cancer cells that are not killed by other forms of treatment, such as surgery, radiation therapy, or chemotherapy. As part of a comprehensive treatment plan, Personalized Vaccines may have the potential to be a curative therapeutic option.

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PERSONALIZED ONCOLOGY PANEL

Champions' provides the cancer patient and treating physician with access to the world's top cancer experts. Champions will convene a panel of renowned experts, selected based on a patient's specific cancer type and condition, from each of the disciplines critical to the patient's case. In a round table forum, the expert panel debates the broad array of options and provides a consensus treatment recommendation to the patient's physician.

Through Champions' services, the cancer patient's treatment team can quickly avail itself of the opinions of the multidisciplinary panel's timely treatment recommendations, saving the cancer patient and the treating physician valuable time in the identification of personalized cancer treatment options.

Once selected, the panel meets in-person to review the patient's case, including a review of the patient's medical information and results of genetic testing. The panel then evaluates conventional and novel treatment approaches, advanced chemotherapeutic drugs, biologics and available clinical trials. Dr. David Sidransky, world renowned oncologist and research scientist, chairs the Personalized Oncology Panel and guides its members to a consensus treatment recommendation. Implementation of the panel's treatment commendations are the responsibility of the patient's physician.

The panel reconvenes at a later date, by teleconference, to review the cancer patient's progress and other developments and, at that time, makes additional treatment recommendations that may be necessary.

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